Coronary Flow Reserve, Inflammation, and Myocardial Strain: The CIRT-CFR Trial.

JACC Basic Transl Sci · 2023 · PMC9998473 · PMID 36908662

Europe PMC DOI

hedged sentences

0.0920

closest p · 1.8× alpha

0.0920

boldest claim

The sentences

a trend toward significanceP = 0.092so close (0.05 < p ≤ 0.1)

We found that lower CFR correlated with measures of increased inflammation (IL-6: r = -0.44; P = 0.002; IL-1β: r = -0.33; P = 0.027) with a trend toward significance for hsCRP ( r = -0.25; P = 0.092).

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highly significantno p-value reported

Thus, a direct and highly significant moderate-strong correlation was present between CFR and GLS only in patients at the lowest median of IL-6 or IL-1β.

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