A meta-analysis of chemokines in vitiligo: Recruiting immune cells towards melanocytes.

Front Immunol · 2023 · PMC9999440 · PMID 36911664

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantP < 0.00001actually significant

12/15 studies (80%) reported significantly higher CXCL10 levels in vitiligo patients compared to controls, resulting in an overall highly significant CXCL10 concentration in the blood of vitiligo patients (P < 0.00001) ( 13 – 20 , 22 , 23 , 25 – 28 ).

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borderline significantP = 0.05actually significant

Only 1/5 reports found elevated circulating CXCL9 levels in active compared to stable vitiligo patients, although the final results of studies investigating CXCL9 in blister fluid were borderline significant (P = 0.05).

also in 11,409 other papers

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