Barely Significant

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highly significantP < 0.00010.0× alphaqualifiedgold
The PADIT risk score was found to be highly significant ( P < 0.0001), with an estimated hazard ratio (HR) and corresponding 95% confidence interval (CI) of 1.28 (95% CI 1.22, 1.33) ( Table 3 ); thus, the relative risk of a major CIED infection increased by 28% for each one unit increase in PADIT risk score.
highly significantP value <0.00010.0× alphaqualifiedgold
A smoothed spline Cox PH model (Figure 3 ) showed a highly significant ( P value <0.0001), mostly linear relationship between patient age and increasing risk for log‐transformed mortality.
highly significantp < 0.00010.0× alphaqualifiedgold
This reactivity pattern was similar for serum and saliva after the second and third vaccination with BNT and showed a highly significant correlation as seen in Figures 3E (r = 0.8879, p < 0.0001) and 3F (r = 0.7384, p < 0.0001). 3.3 Vaccination induces neutralizing IgG but not IgA in the saliva We further performed a neutralization assay with the authentic SARS-CoV-2 virus variant EU1/B.1.177 ( Figure 4 ).
highly significantp = 0.00010.0× alphaqualifiedgold
There was no significant change in the expression of pMx-MGT Ang II cells (676.3 ± 421.3 pixels/cell; Figure 4 C,F) and pMx-MGT ET-1 cells (675.5 ± 409.1 pixels/cell; Figure 4 D,F), but a highly significant upregulation of MCP-1 was measured in the Isl1 + Sca1 + ckit + pCPCs stimulated with Ang II (1541.0 ± 880.9 pixels/cell, p = 0.0001; Figure 4 E,F). 3.4.
highly significantp < 0.00010.0× alphaqualifiedgold
A highly significant difference ( p < 0.0001) for this global pressure is observed between athletes with a perceived negative impact on performance over more than three days after full vaccination, for whom the global pressure was 80 (60–100) compared to 30 (0–70) for the athletes who did not perceive a negative performance impact or for less than three days.
highly significantp<0.00010.0× alphaqualifiedgold
Anatomical parameters: In the experimental group, the measurements of KGB, DAP and DBP were all reduced and DCM and DTM were all increased and observed to be symmetrical for both the legs at week 12 and were highly significant (p<0.0001) when compared to the control group ( tables 2A - 3B ) But they were not significant and remained as asymmetrical in the control group at week 12 when compared to week 0 ( tables 2A - 3B ).
highly significantp < 0.00010.0× alphaqualifiedgold
By contrast, in NT animals, the success rate following the US stimulation of their visual cortex dropped to 38.1 ± 18.5% (s.d.), and the difference with the success rate following LS on the fourth day was highly significant ( p < 0.0001) (Fig. 6d and Extended Data Fig. 6 ).