Barely Significant
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“a decreasing trend”

47,181 sentences · 47,181 papers · 78,848 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Doxorubicin causes insulin resistance and hyperglycaemia by disrupting adenosine monophosphate activated protein kinase (AMPK) signaling pathways.[ 5 ] Haemodynamic instability (not requiring ionotropic support) during secondary cytoreduction owing to blood loss and massive fluid shifts lead to metabolic acidosis, which was exaggerated during HiPEC with a decreasing trend in pH and bicarbonate [ Table 1 ].
Lower healthy tissue uptake (toxicity) with loading dose When the total antibody dose increased from 0.3 mg kg −1 to 2.6 mg kg −1 , muscle uptake of the antibody–dye conjugate (%ID kg −1 ) showed a decreasing trend (Fig. 2a ), suggesting that co-administration of unlabeled antibody saturates the estimated glomerular filtration rate (EGFR)-binding sites in the muscle and thus reduces the target-mediated uptake (relevant for ADC toxicity) in healthy tissue.
The results are shown in Figure 9 ; it can be seen that the CO conversion and CH 4 selectivity of the DIP-Ni/Al 2 O 3 catalyst are basically maintained at around 90% with the increasing WHSV, indicating that the catalytic activity and selectivity of the catalyst prepared by the dipping method is relatively stable. However, the CO conversion and CH 4 selectivity for the SG-Ni/Al 2 O 3 catalyst show a decreasing trend; the CO conversion decreases from 81.9 to 62.7% and CH 4 selectivity decreases from 73.4 to 56.2% when the WHSV increases from 6000 to 14,000 mL g –1 h –1 .