Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

The prepandemic period was analyzed in most of these studies with no changes in BZD and/or hypnotic prescriptions during the pandemic, showing different trends of prescriptions across areas: an increasing trend in Poland [ 46 ], a decreasing trend in Canada [ 57 ], and no change in the Scania region in Sweden during the time period before COVID-19 [ 58 ].
This seemingly produces two segments of different slopes: the first extends from January 2007 to the end of September 2009 (pre-intervention period), showing an increasing trend, and the second extends from the beginning of October 2010 to the end of December 2013 (post-intervention period), showing a decreasing trend.
The levels of mitochondrial fusion and fission proteins corresponding to the exposed group showed abnormality: the fission protein dynamin-related protein 1 ( Drp1 ) showed an increasing trend, and the fusion proteins optic atrophy 1 ( OPA1 ), mitofusin 1 ( Mfn1 ), and mitofusin 2 ( Mfn2 ) showed a decreasing trend ( Figure 3B and 3C ).