DISCUSSION Pre-clinical animal models that can recapitulate the metastatic process and resemble specific molecular subtypes of human BC as well as facilitate identification and validation of candidate drug target genes are greatly desired since gene expression patterns in the mouse models shows extraordinarily significant correlations with those of the human conditions [ 38 ].
Nanoparticles are organic or inorganic materials that can be synthesized through various physical, chemical and biological methods, and they possess particle sizes in the range of 1–100 nm with large surface area to volume ratio which makes them extraordinarily significant ( Seil and Webster, 2012 ; Iravani et al., 2014 ).
This sad argument is even reinforced by the positive sign for the coefficients of the interaction term for both the depression and domestic violence search, which is not statistically significant for domestic violence but extraordinarily significant for depression (at 1% confidential level).
Thus, improving children’s nutritional status and lessening the prevalence of malnutrition to advance their physical and mental improvement would be extraordinarily significant [ 20 ].
Second, overlapping or linked SNPs spanning the entire APOE and TOMM40 region were reported to be associated with sporadic AD case-control analyses in all published GWAS with extraordinarily significant p-values, as clearly demonstrated in Table 1 [ 29 , 49 – 54 ].
43 One women’s health worker who I interviewed in 2013 said that “symbolically I think it’s extraordinarily significant in that it says women are adults who are capable of making decisions about their own lives and their own bodies.” 44 Another, who works with young people, stated that “from an education perspective it has been quite an improvement in relation to being able to clearly state what their rights to abor
However, the SEM estimation based on homogeneous_CS as in Eq (3) has a completely different trend (constant SEM), thus the endpoint become extraordinarily significant and less significant at week 1 and week 7.
Last but not least, it is extraordinarily significant to further improve the resolution of the testing instrument and the stability of the testing environment to ensure that the error caused by the testing process is minimized.