“might be significant”

Third, because the COREA‐AMI registry was not designed to observe clinical outcomes according to BB duration, our analysis might be underpowered to detect a clinically significant difference in the outcomes, and nonsignificant findings might be significant in a larger cohort of patients.

Since the TNM stage of patients might vary greatly after nCRT, there might be significant variations in prognosis based on cTNM stage.

Therefore, the interference of serum TgAB in Tg-FNAB measurement might be significant when serum TgAB are higher and differences in cutoffs for both measurements should be considered in those situations.

Methane production from hexadecane ( Table 2 ), a long-chain alkane, in some methanogenic slurries (e.g., Mercator MV) demonstrated that methanogenesis from saturated hydrocarbons might be significant in MV sediments as previously shown in other anoxic environments ( Zengler et al., 1999 ; Fowler et al., 2016 ).

However, there might be significant concerns about whether they will be able to maintain their visual function as they age.

Even though SMD was used to understand DMDD in the present review, the relatively small difference between DMDD and SMD criteria might be significant and becomes evident when examining youths on a group level.

Thus, we conclude that, even if the benefits of second-line therapy are limited among unselected patients in the real-world practice, they might be significant in some subgroups of patients ( 22 , 23 ).

The fact that 1,25(OH) 2 D 3 significantly inhibited lipid accumulation in cells cultured in a steatosis-inducing medium ( Figure 4 ) corroborated the involvement of the genes and metabolic pathways identified in the zebrafish model ( Figure 3 and Supplementary Tables S1 and S3 ) and the idea that these pathways might be significant targets for preventing and treating NAFLD in humans.

The findings suggest that disruptions in the structure and function of the mentioned genetic factors such as polymorphic and haplotype variants of PAX9 , MSX1 , AXIN2 , and IRF6 genes, which play a direct role in tooth and periodontal tissue development, might be significant factors in tooth impaction in individuals with genetic variations.

In addition, an ongoing, long-term extension trial ( NCT01500551 , https://classic.clinicaltrials.gov/ct2/show/NCT01500551?term=01500551&draw=2&rank=1 ) might be significant in observing the long-term safety of tofacitinib in paediatric patients.

This possible scenario of altered vasa in SV in post-COVID-19 patients might be significant, though difficult to judge at this stage.

atrial fibrillation, ischaemic heart disease, peripheral vascular disease), the risk of recurrent haemorrhage in individuals with familial CAA presenting with or without ICH might be significant, although definitive natural history data are lacking.

27 , 28) As non-orthopedic studies have demonstrated that FIR could promote access of blood flow and wound healing, there might be significant differences in postoperative pain, ROM, functional scores, and tendon-to-bone healing for patients with large-sized cuff tears depending on whether FIR is applied or not.

To determine whether this 2-fold increase might be significant, we performed a simulation study.

In addition, there might be significant concerns about the legitimacy to deal with crop-saving-embankments and weather forecasting information for flash flooding adaptation.

In addition, the study compares data with previous studies conducted in other countries like Canada, but there might be significant cultural, educational, or socio-economic differences that could influence the results.

There are now a handful of drugs targeting the ubiquitin system being approved by the US FDA, and further testing of their effects on NLRP3‐related diseases might be significant for development of targeting therapy. 5.4.

At the same time, a cohort analysis utilizing the cBioPortal platform indicates that WNT4 might be significant for the growth of various histological tumor types as among a large group of EC patients, an alteration in WNT4 expression was found to be evident within the serous carcinoma.

This suggests that the EGFR-GEP100-ARF6 pathway might be significant in the process of acquiring a malignant phenotype in breast cancer cells.

However, one may speculate that, in view of the fact that GTR was used in complicated cases, the difference might be significant if these cases were treated without GTR.

The presence of cysteine residues at the ends of these two segments might be significant for maintaining the overall active conformation of the protein and also for controlling the active site dynamics, specifically involving the residues Trp126, Leu127 and His131.

Additionally, the degree of color variation might be significant at a high mixture level.

25 , 26 As postoperative pulmonary events are known complications after lung cancer surgery, 27 the impact of severe obesity (BMI ≥ 35 kg/m 2 ) might be significant in patients undergoing this surgery.

The interaction between leaf nutrient concentration and transpiration is usually absent or minor for N and P, but it might be significant for Ca or Mg ( Shaner and Boyer, 1976 ; Engels and Marschner, 1993 ; Marschner, 2012 ).

According to the study, if the healthcare industry can catch up technologically with other sectors, there might be significant gains in innovation, productivity, and profit. 28 The primary use of blockchain lies in the management of assets where the smart contracts will be embedded with the assets, and it will define what is owned by whom at a point in time. 31 The working of the transaction occurs on a set of various data inputs; they can define as per the requirement.