“might be significant”

This indicates that they might be significant drivers of the ageing process and preservation of their physiological functions over time will clearly support neuronal health.

Similarly, Pringle et al 38 did not include out-of-pocket expenditures which might be significant and could influence the intervention attendance levels (apart from the cost-effectiveness of the intervention).

It is widely used for a vast number of ailments and might be significant in the management of SCD [ 197 ] ( Table 3 ).

One can also hypothesize that the relative contribution of centrally planned compensation is greater in fast and highly skilled movements, while spinal compensation might be significant in everyday movements such as reaching; or that the spinal contribution is greater early on in development, while being gradually replaced with more precise central corrections acquired by adaptive processes in the CNS.

To capture the experiences of all individuals for whom the research might be significant, priority-setting stakeholders included academics/researchers, government decision-makers/policymakers, advocates, health and social service providers, representatives of professional associations, funders, trans community members and survivors.

The latter results might be significant for biomedical applications of MNPs.

Specifically, there might be significant differences in resource distributions between female and male household members that could point to important gender gaps in a society (Harttgen et al. 2013 ), but that the present analysis could not detect.

Nevertheless, there might be significant conformational differences between adducts, even if the crystal structures of CDDP- and oxaliplatin-GG adducts are similar, e.g., cisplatin could cause a disruption of cellular activity through binding to a more sensitive region of the genome, such as the telomeres [ 29 ].

Moreover, as research on other mobile health app has shown, there might be significant differences in uptake by age, income, education, health literacy, self-reported health, and intention to engage in healthy behavior [ 18 ].

Conversely, the shoulder joint and its position sense might be significant proprioceptive elements during reaching.

Extending the leukemogenesis model of MPAL, we deduced that genetic lesions might occur at an earlier HSPC stage in adult T-ALL, resulting in abnormal proliferation/differentiation/apoptosis of myeloid and lymphoid lineages, which might be significant in explaining the difference in prognosis and treatment responses observed between pediatric and adult T-ALL ( SI Appendix , Fig.

We hypothesized that intra-population (temporal) genetic variance and temporal instability might be significant among recently founded, historically small, or artificially propagated Rainbow Trout populations similar to that seen in their native range [ 45 , 46 ].

Second, animal numbers used in this study are small and it might well be that minor differences in stroke volume might be significant if higher animal numbers were used.

In the last few days of 1849 – he was even at work on Christmas Day and missed going out with his friends Debus and Bromeis on New Year's Eve – it struck him that the cleavage rather than the optic axis of the crystal might be significant, an idea that would become the basis of his beliefs about the importance of molecular structure, and would become particularly significant in his later work on glaciers.

Furthermore, we used the kinetic parameters obtained in the present and previous work to model the effect of TKI-induced inhibition of creatinine transporters on SCr in order to assess whether it might be significant in relation to the clinical diagnosis of TKI-induced renal failure.

This might be significant in scenarios where the communication bandwidth is limited.

14 However, we believe that there might be significant antibiotic resistance to the recommended treatments, and as a result, the likelihood of treatment failure is rising with the continued empirical use of these medications.

A common feature of tumor vessels studies is that the investigators focus on microvessel density overlooking other parameters that might be significant, such as the size and shape of the microvessels [ 8 ].

The Cox regression model was used for multivariate analysis, with adjustments for characteristics that might be significant prognostic factors according to the univariate analysis.

The interaction of the calcium response induced by P2X7 receptors and BCR stimulation might be significant for the modulation of the immune response.

Moreover, given a large proportion of immunosuppressed participants (83.8% had ≤500 CD4+ cells/mm 3 ), the positive effect of ART on HRQoL through the expected considerable reduction in plasma HIV RNA and restoration of immunologic function might be significant.

Hence, approaches designed to induce β-Cell formation might be significant therapeutic options for the management of T2D.

The authors of the present study assumed that the age of the patient might be significant in terms of the intensity of emotions during hospitalisation in the ICU.

This role might be significant given the high BTV seroprevalence in African dogs reported in previous studies (20%–21%) [ 12 , 24 ].

While there might be significant variance in intelligence across TS patients, only slight impairments in general intelligence are usually reported.