Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model.

Cells · 2023 · PMC10001065 · PMID 36899837

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did not reach statistical significancep > 0.05actually significant

Treatment of mdx mice with 30 mg/kg/wk of tcDNA-ASO for 12 weeks improved all parameters, although the differences did not reach statistical significance ( p > 0.05 analyzed by one-way ANOVA).

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