MAPK pathway activity as measured by DUSP6 expression showed a trend towards suppression in the PR group (Supplementary Fig. 2 ).
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A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma.
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MAPK pathway activity as measured by DUSP6 expression showed a trend towards suppression in the PR group (Supplementary Fig. 2 ).