Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma.

In comparison with untreated samples, 3 of 4 post-therapy samples exhibited increased degranulation responses (CD107a/b) and elevated production of IFN-γ and TNF-α ( Figure 4A ), although the findings did not reach statistical significance due to the small number of samples.

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