Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells.

Endocrinology · 2023 · PMC10016038 · PMID 36774542

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near-significantno p-value reported

7 ), and found a near-significant increase in cAMP response to 100 nM GIP compared with GLP-1 stimulation in wild-type INS-1 832/3 cells ( Fig. 7A ), a tendency replicated in primary mouse islet beta cells ( Fig. 7B ).

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