“near-significant”

After re-fitting the most significant SNP (OCU4:13,434,448, p = 1.31e-12) as a covariate, another near-significant SNP (OCU4:11,344,946, p = 7.03e-07) was still present.

Significant or near-significant differences were found in the localization of the primary tumor (extrapelvic localization 86.4 vs. 61.6%, p = 0.0002) and the rate of applied MA (13.6 vs. 24.2%, p = 0.0686).

Results In comparison with placebo, ginger supplementation resulted in significant or near-significant reductions in the frequency (-23.63 ± 5.36 vs. 14.81 ± 2.78, P < 0.001) and severity (-24.15 ± 5.10 vs. 11.39 ± 3.23, P < 0.001) of constipation, the frequency (-12.41 ± 3.75 vs. 3.75 ± 1.82, P < 0.001) and severity (-13.43 ± 4.91 vs. 6.88 ± 2.69, P = 0.001) of nausea, the frequency (-9.31 ± 4.44 vs. 1.56 ± 4.05, P = 0.098) and severity (-11.57 ± 5.09 vs. 3.97 ± 3.99, P = 0.047) of bloating, and the severity of abdominal pain (-5.69 ± 3.66 vs. 3.43 ± 3.26, P = 0.069).

Rearing events also showed significant or near-significant increases when analyzed separately within binned intervals (0 to 10 min, P = 0.002; 10 to 20 min, P = 0.046; 20 to 30 min, P = 0.074) ( Fig. 3 C ).

Feces At all three time points, a significant or near-significant enrichment was found in biopterin metabolism (day 7: p = 0.004; day 28: p = 0.055; term: p = 0.010).

( 55 ) also examined NO and NOx, with significant and near-significant association between increase in NO (OR 1.46; 95% CI 1.11–1.93; p = 0.008) and NOx (OR 1.24, 95% CI 0.99–1.53; p = 0.052) concentrations and AE-IPF.

Levene’s test for homogeneity of variance produced a near-significant result (F(3, 64) = 1.63, p < 0.01), suggesting that the variances across groups were marginally different and necessitating careful interpretation of results.

Using the Cox Proportional Hazards model, accounting for MMP-11 expression and other vital clinical and pathological prognostic factors, only two variables showed significant or near-significant associations with reduced DFS: elevated Ki67 (HR = 1.12, 95% CI [1.03–1.21], p = 0.01) and high MMP-11 expression (HR = 1.02, 95% CI [1.00-1.04], p = 0.05).

P200 There was a main effect of orientation ( F (1,17) = 28.09, p < .001, η 2 G = .120), a main effect of palate (F(1,17) = 18.06, p < .001, η 2 G = .017), and a near-significant orientation x palate interaction (F(1,17) = 8.06, p = .011, η 2 G = .005) on the amplitude of the P200.

The total mean MPT difference was -2.8 mN (95% CI = -6.8, -1.2, back-transformed), indicating near-significantly increased hyperalgesia (gain of sensory function) for punctate mechanical stimulation (P = 0.02).

Analyses of paired grafts in the same rabbits showed statistically significant or near-significant mean reductions of total and percentage ORO-positive intimal areas in HDAdApoAI grafts (19% and 14%; p = 0.02 and 0.05, respectively) ( Figures 4 E and 4F; Table 2 ).

The SI parameter showed a near-significant difference ( p = 0.026) between the two groups, just missing the p < 0.025 confidence level.

Here, compared with placebo, we observed absolute decreases in average urinary putrescine, the direct product of ODC ( Figure 1 A), with DFMO treatment for all treatment groups, with significant or near-significant differences in the 500 (p = 0.03) and 1,000 mg/m 2 (p = 0.05) dosing groups.

In the asthma group, FENO 50 exhibited significant or near-significant negative correlations with pulmonary function parameters such including FEV 1 /FVC (ρ = −0.241, P < 0.05), MMEF (ρ = −0.239, P < 0.05), MEF50 (ρ = −0.029, P < 0.05) and MEF25 (ρ = −0.215, P = 0.054).

Notably, the albumin to bilirubin (ALBI) ratio demonstrated a near-significant prediction of PFS with grade 1 scores protective for PFS (HR 0.13, 95% CI 0.15–1.08, p = 0.05) ( Table 3 ).

fusiforme and the control over time, there was a near-significant difference ( p = 0.05). 3.2.

Individually, the LN group showed a near-significant reduction in office systolic BP (−4.39 ± 2.19, p = 0.05), whereas the HN group alone showed no reduction in office systolic BP (−1.30 ± 2.92 mmHg, p = 0.66).

Post-hoc analysis showed near-significant differences of MMSE scores between level 1 and 2 ( p = 0.05), and between level 1 and 3 ( p = 0.07), and no difference between level 2 and 3 ( p > 0.99).

Correlation between ADC, Tumor Grades, and Clinicopathological Variables There was a near-significant difference ( p = 0.050) between the ADCs of well (mean p10 1355 μm 2 /s), moderately (mean p10 1052 μm 2 /s), and poorly differentiated tumors (mean p10 1052 μm 2 /s).

However, because a near-significant effect was observed in the latter case, we report that a significant difference (post-hoc Conover test, p<0.05) was present between patients on DMARD therapy (median 3, IQR 2-6) and patients receiving glucocorticoids (median 5, IQR 3-7) and combined NSAID + glucocorticoid therapy (median 5, IQR 3.3-7).

Unlike in the HMC3 cells, LY329 and Triagonist significantly or near-significantly (respectively) reduced ROS in the presence of H 2 O 2 in SH-SY5Y cells ( Figure 2 D; LY329 p < 0.05, Triagonist p = 0.0582). 3.3.

The regression model included variables that had a significant ( p < 0.05) or near-significant (0.1 ≥ p ≥ 0.05) association with likely high stress and low resilience in the chi-square test/Fisher’s exact test analysis.

There was no significant association of the ESS with minimum monocular or binocular LCLA, but a near-significant effect ( p ≈ 0.05) was observed for the IOD, shown in Table 3 .

When AYA patients were stratified by SIL spatiotype regardless of ICI outcome, the SIL high group showed a trend of longer OS and a near-significant longer PFS ( P = 0.0504) compared to SIL low group (Supplementary Fig. 5f, g ).

For signature 2 there was a near-significant group*time interaction ( F = 3.1, P = .0510) and expression was similar in patients and controls at baseline ( P = .8222) but increased significantly from baseline to month 12 ( P = .0005) and month 24 ( P < .0001) in patients, but not in controls at month 12 ( P = .2471) and month 24 (0.4414).