The proportional reductions in colon cancer–specific mortality (RR = 0.74 [95% CI, 0.52 to 1.05, P = .095]), and all-cause mortality (RR = 0.76 [95% CI, 0.55 to 1.06, P = .104]) were of similar magnitude but did not reach statistical significance.
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Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial.
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