Parallel to total knockout, Chr4 Δ70 kb /Δ70 kb BM-transplanted mice also showed a tendency to increase blood leukocyte number (12.09 ± 3.65 × 10 9 cells/L) compared with WT BM recipients (9.42 ± 2.82 × 10 9 cells/L), but the difference between the groups did not reach statistical significance ( P = 0.087; Table 2 ).
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Deletion of the murine ortholog of human 9p21.3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity.
1
0.0870
0.0870