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Characterization of a mutant <i>samhd1</i> zebrafish model implicates dysregulation of cholesterol biosynthesis in Aicardi-Goutières syndrome.

Front Immunol · 2023 · PMC10025490 · PMID 36949945

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However, although variable, the samhd1 Δ23/Δ23 larvae appeared to display increased expression of each ISG, although this did not reach statistical significance.

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