In 3xTg-AD mice, EGR1 and AChE mRNA levels were significantly positively correlated for the entire group and within each age group or sex, while this correlation only showed a trend in females of 11–12 months-old.
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Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens.
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