Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models.

NPJ Vaccines · 2023 · PMC10033289 · PMID 36949051

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

did not reach statistical significanceP = 0.061so close (0.05 < p ≤ 0.1)

RSV preF protein alone also induced a boost response of 17-fold; however, this response did not reach statistical significance ( P = 0.061, paired t test) due to the low number of animals ( n = 4) and high variation in this group.

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