Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.

Nat Commun · 2023 · PMC10033639 · PMID 36949040

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

trending towards significancep = 0.06so close (0.05 < p ≤ 0.1)

A difference in survival, trending towards significance, was seen between WT ( n = 11) relative to CD8 KO mice ( n = 9; p = 0.06), implanted with kinome KO GL261 glioma cells (Fig. 1c ), suggestive of CD8 T-cell-mediated selection in WT mice implanted with kinome KO GL261 glioma cells.

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