Comparison of clinical outcomes between aggressive and non-aggressive intravenous hydration for acute pancreatitis: a systematic review and meta-analysis.

However, the significantly increased risk of mortality in the aggressive intravenous hydration group was only observed in severe AP (2 RCTs; 191 participants; pooled RR: 2.45, 95% CI: 1.37, 4.40; I 2 : 0%), while in non-severe AP the results remained similar but did not reach statistical significance (7 RCTs, of which only 3 contributed mortality events; 762 participants; pooled RR: 2.26, 95% CI: 0.54, 9.44; I 2 : 0%).

also in 111,027 other papers