When comparing only the PanIN lesions, the N4 − / − PKC mice tended to display fewer PanIN-3 lesions than the PKC mice at both the ages of 2- and 5-month timepoints, albeit the differences did not reach statistical significance ( P = 0.054 and P = 0.169, respectively; Supplementary Fig.
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Inactivation of <i>Notch4</i> Attenuated Pancreatic Tumorigenesis in Mice.
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