Interestingly, we also found a nearly significant reduction of the transcript levels of the master regulator of the germinal center (GC) reaction, Bcl6 , in splenic tissues of Nlrp12- deficient mice ( Figure S3A ).
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<i>Nlrp12</i> deficiency alters gut microbiota and ameliorates <i>Fas<sup>lpr</sup></i> -mediated systemic autoimmunity in male mice.
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