Although oliceridine resulted in a reduction in RSB (0.04–0.8 hours vs 1.1 hours for morphine), it did not reach statistical significance. 41 APOLLO-2 was another phase III, multicenter, randomized, controlled clinical trial in 401 patients with moderate to severe pain following abdominoplasty that used the same dosing regimens and endpoints as the previous study.
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Oliceridine for the Management of Moderate to Severe Acute Postoperative Pain: A Narrative Review.
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