The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E<sub>2</sub>, enhances VEGFR2 activation and promotes angiogenesis.

J Biol Chem · 2023 · PMC10040730 · PMID 36813233

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did not reach statistical significanceno p-value reported

Treatment with VEGF 165 positive control ± vatalanib showed a similar trend although the effects did not reach statistical significance except for the effect on the area of the rings formed.

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