Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 <i>via</i> methyl-dependent changes in epigenetic markings.

However, in cultures of the SEV group, the reduction of CCL3 by B12 did not reach statistical significance and intracellular IL-1B levels were very low, close to the detection limit of the technique, suggesting that, in severe COVID-19, leukocytes are more prone to promptly export IL-1B.

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