Homing of vertebral-delivered mesenchymal stromal cells for degenerative intervertebral discs repair - an in vivo proof-of-concept study.

JOR Spine · 2023 · PMC10041374 · PMID 36994461

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showed a trendno p-value reported

31 , 51 , 52 Although our study showed a trend of enhanced MSC migration into degenerating IVD, the overall rate of GFP + cells detected was generally low.

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an increasing trendno p-value reported

The DT condition showed an increasing trend in histological scoring; nonetheless, the scores were neither significantly worse than the REF, HS, or HT conditions, nor showed significant improvement compared to the DS condition, overall suggesting at most a trend of limiting the induced degeneration compared to DS.

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