Multivariable MR analysis of pancreatitis In the multivariable MR model, smoking (OR = 1.287, P = 0.026), education level (OR = 0.441, P = 1.78E-09), household income (OR = 0.436, P = 0.002), IBD (OR = 1.052, P = 0.036) and triglycerides (OR = 1.202, P = 0.009) had similar significant causal effects on AP after adjusting for genetically predicted cholelithiasis, whereas LDL_C, total cholesterol, BMI, whole body fat mass, hip circumference and waist circumference did not reach statistical significance ( Figure 5A ).
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Causal associations between modifiable risk factors and pancreatitis: A comprehensive Mendelian randomization study.
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