Comparisons of Cytokines, Growth Factors and Clinical Efficacy between Platelet-Rich Plasma and Autologous Conditioned Serum for Knee Osteoarthritis Management.

However, significantly more patients in the ACS group still felt pain and needed oral medicine compared to those in the PRP group at the end of the study, this may be due to more patients with worse pain at baseline choosing ACS administration, even the difference between the two groups did not reach statistical significance, which may relate to the small sample size.

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