Barely Significant
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FBXO11 governs macrophage cell death and inflammation in response to bacterial toxins.

Life Sci Alliance · 2023 · PMC10053445 · PMID 36977592

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As expected, treatment of WT and FBXO11 −/− macrophages with BI-3802 resulted in loss of BCL-6 and increased CD40 protein and mRNA levels, although this did not reach statistical significance suggesting other mechanisms are at play ( Fig 6D and E ).

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