The Fibrosing Alveolitis in Scleroderma Trial (FAST) was another placebo-controlled trial using intravenous cyclophosphamide and oral prednisolone followed by maintenance azathioprine, which demonstrated a trend towards treatment benefit based on differences in FVC, although the difference did not reach statistical significance [ 98 ].
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Diagnosis and Pharmacologic Management of Fibrotic Interstitial Lung Disease.
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