Inappropriate Expression of PD-1 and CTLA-4 Checkpoints in Myeloma Patients Is More Pronounced at Diagnosis: Implications for Time to Progression and Response to Therapeutic Checkpoint Inhibitors.

While a decline of PD-1 was observed in the whole population of NDMM CD4 + T cells, including both Teff and Treg subsets, the loss of PD-1 was more pronounced in Treg cells ( p = 0.016) ( Figure 1 b); in Teff cells, a decrease of PD-1 was of borderline significance ( p = 0.08) ( Figure 1 b).

also in 446 other papers

Although some differences in PD-1 expression between patient groups were observed, they did not reach statistical significance.

also in 50,127 other papers