Clinical efficacy and safety of interferon (Type I and Type III) therapy in patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials.

PLoS One · 2023 · PMC10057835 · PMID 36989209

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did not reach statistical significanceno p-value reported

Although IFN therapy tended to reduce 28-day mortality in the subgroup of patients with moderate-to-severe COVID-19, the difference did not reach statistical significance (pooled RR = 0.60, 95% CI: 0.11–3.45, I 2 = 31%).

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