TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A.

PLoS Biol · 2023 · PMC10057836 · PMID 36930682

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did not reach statistical significanceno p-value reported

Interestingly, GFP-TDP-43 N-term del , GFP-TDP-43 N-term mut , but not GFP-TDP-43 E17R , showed reduced binding to UNC13A cryptic RNA, although this reduction did not reach statistical significance ( Fig 2B ).

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