NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol.

Int J Mol Sci · 2023 · PMC10058228 · PMID 36982904

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highly significantno p-value reported

Figure 6 a (right) also illustrates how the levels of activated NOTCH (cleaved at Val1744) showed a highly significant increase at 6 h post LPS treatment.

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showed a trendno p-value reported

Indeed, the assessment of MMP-13 mRNA level in C28/I2 cells (6 h after LPS) showed a trend that confirmed the pivotal role of JNK, and was suggestive of the contribution of this pathway for MMP-13 expression ( Figure 6 b).

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