Chemical Composition and Biological Activities of Essential Oils from <i>Origanum vulgare</i> Genotypes Belonging to the Carvacrol and Thymol Chemotypes.

As compared to the control, treatment with CAR1 induced a mild gene expression downregulation of the IkBα and IL-6 genes of the NF-kB pathway; however, this downregulation did not reach statistical significance, probably due to great data variability ( Figure 6 A).

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When the cells were pre-treated with THY5 before TNF-α addition, the gene expression levels of all analyzed genes were similar to TNF-α, even if an increasing trend could be observed for inflammatory IL-1α, IL-6 and IL-8 cytokines ( Figure 6 B). 3.

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