Magnetic resonance brain volumetry biomarkers of CLN2 Batten disease identified with miniswine model.

Sci Rep · 2023 · PMC10060411 · PMID 36991106

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a weak trendno p-value reported

While correlation between SubC and MRI brain volumetry did not reach statistical significance for this small sub-cohort, there was a weak trend of lower ICV and GM volumes at higher SubC values for CLN2 R208X/R208X miniswine at 17-months-of-age (Supplementary Fig. 1 ).

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did not reach statistical significanceno p-value reported

While correlation between SubC and MRI brain volumetry did not reach statistical significance for this small sub-cohort, there was a weak trend of lower ICV and GM volumes at higher SubC values for CLN2 R208X/R208X miniswine at 17-months-of-age (Supplementary Fig. 1 ).

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