Mesenchymal stem cell-derived secretome enhances nucleus pulposus cell metabolism and modulates extracellular matrix gene expression <i>in vitro</i>.

On the other hand, following IL-1β pretreatment, cell viability dropped to 83.8% ± 20.5% but was significantly increased following treatment with BM-MSCsec (112.5% ± 23.9%, p = 0.009) and ADSCsec (104.3% ± 26.2%), even if the latter did not reach statistical significance ( Figure 4B ).

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