In the entire cohort, age (HR = 1.031, 95% CI 1.013–1.049, p = 0.001), ECOG (HR = 2.176, 95% CI 1.644–2.880, p < 0.001), T stage (HR = 1.315, 95% CI 1.872–1.613, p = 0.009) and concomitant systemic treatment (HR = 0.511, 95% CI 0.333–0.783, p = 0.002) were prognosticators for OS, while the prognostic value of peritherapeutic antibiotic administration (HR = 1.407, 95% CI 0.995–1.990, p = 0.053) reached borderline significance (Table 3 ).
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The influence of antibiotic administration on the outcomes of head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiation.
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