Low-dose IL-2 mitigates glucocorticoid-induced Treg impairment and promotes improvement of SLE.

Signal Transduct Target Ther · 2023 · PMC10068597 · PMID 37009820

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did not reach statistical significanceno p-value reported

However, the upregulation of ICOS in Tregs from SLE patients did not reach statistical significance, which was consistent with the report that Tregs in SLE patients were less sensitive to IL-2 than those from healthy people 8 (Supplementary Fig. 2b ).

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