NAD<sup>+</sup> repletion with niacin counteracts cancer cachexia.

Nat Commun · 2023 · PMC10070388 · PMID 37012289

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NRK2 gene expression decreased in weight-stable cancer patients and showed a trend toward further downregulation in cachectic patients compared to weight-stable ones (Fig. 2a ) confirming that NRK2 loss is a novel common alteration in CC.

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