Longitudinal home-cage automated assessment of climbing behavior shows sexual dimorphism and aging-related decrease in C57BL/6J healthy mice and allows early detection of motor impairment in the N171-82Q mouse model of Huntington's disease.

Front Behav Neurosci · 2023 · PMC10073658 · PMID 37035623

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difference was apparentp < 0.01actually significant

This difference was apparent as early as 8 weeks when the animals showed no overt signs of the disease onset ( Figure 3E , n = 8 WT/11 Hemi, p < 0.01).

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