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Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease.

Sci Rep · 2023 · PMC10079843 · PMID 37024714

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Levels of PDE protein were found reduced in P30 Npc1 nmf164 mice by western blot but did not reach statistical significance (Supplementary Fig. 4 ).

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