This clear alteration in microbiota composition was confirmed by quantification of the unweighted Unifrac distance, exhibiting highly significant impact of CMC and P80 consumption on microbiota composition compared with water-treated mice ( figure 3C, D ).
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<i>Akkermansia muciniphila</i> counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism.
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While a trend of emulsifiers resulting in elevated flagellin (FliC) and LPS was observed, it did not reach statistical significance ( online supplemental figure S4A, B ).