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Aggrelyte-2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia.

Aging Cell · 2023 · PMC10086532 · PMID 36823285

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The WS content was 13.2% higher ( p < 0.01) in the aggrelyte‐2‐treated human lenses than in the untreated controls (contralateral lenses, Figure 4i ), but the difference (4.6% higher) did not reach statistical significance when compared to the aggrelyte‐2C‐treated lenses.

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