Pharmacokinetics of a single dose of Aficamten (CK-274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model.

J Vet Pharmacol Ther · 2023 · PMC10099566 · PMID 36382714

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did not reach statistical significanceno p-value reported

Left ventricular outflow tract Vmax, peak pressure gradient, and the number of obstructed cats were lower after aficamten (2 mg/kg), but these parameters did not reach statistical significance.

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