Constrained catecholamines gain β<sub>2</sub>AR selectivity through allosteric effects on pocket dynamics.

Nat Commun · 2023 · PMC10104803 · PMID 37059717

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did not reach statistical significanceno p-value reported

7 ), although this difference did not reach statistical significance, it is consistent with MD simulations of c-Epi binding to the orthosteric site of β 1 AR.

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