Influence of time from admission to norepinephrine administration and volume of fluids received on outcomes of patients meeting sepsis-3 criteria: a retrospective study using the MIMIC-IV database.

Patients in quartile 2 in the early NE group had significantly lower ICU length of stays (difference in days −1.70 (95% CI −2.82 to –0.58)) while in other groups there were lower ICU length of stays which did not reach statistical significance ( figure 5 ).

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