Structural MRI in Migraine: A Review of Migraine Vascular and Structural Changes in Brain Parenchyma.

42 In contrast, when examining patients with MWoA, Xie et al (2018) observed a generally higher incidence of WMH compared to patients with MA, but this result did not reach statistical significance. 43 Palm-Meinders et al (2012) showed that specifically female patients with MWoA possessed higher levels of deep WMH compared to controls, whereas Kruit et al (2010) found that female patients with migraine independent of subtype exhibited increased levels of deep WMH. 44 , 45 However, there are some conflicting findings on the relationship between WMH, migraine, and other factors, with some papers finding no significant association of WMH progression with different migraine clinical characteristics.

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