Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model.

Antimicrob Agents Chemother · 2023 · PMC10112056 · PMID 36920217

Europe PMC DOI

hedged sentence

0.1190

closest p · 2.4× alpha

0.1190

boldest claim

The sentences

did not reach statistical significanceP = 0.119not close (p > 0.1)

After 4 weeks of treatment, compared to BPaL, S587 25 PaL ( P = 0.0021) and S587 25 PaU ( P < 0.0001) had superior bactericidal activity, while the difference with S587 25 PaO did not reach statistical significance ( P = 0.119) ( Table 5 ).

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