Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2.

Front Oncol · 2023 · PMC10114587 · PMID 37091157

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We observed that the wildtype of the LOXL4-overexpressing MDA-MB-231 subline showed a trend of dampened cell growth in the orthotopic xenograft mouse model compared to the control GFP-overexpressed cells ( Supplementary Figure S2E ).

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